Role for Endogenous BDNF in Endocannabinoid-mediated Long-Term Depression at Neocortical Inhibitory Synapses BDNF regulates endocannabinoid-mediated plasticity
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چکیده
process. This article is distributed under the terms of the Creative Commons Attribution License (http:// creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Copyright © 2015 Society for Neuroscience Research Article: New Research | Neuronal Excitability Role for Endogenous BDNF in Endocannabinoid-mediated Long-Term Depression at Neocortical Inhibitory Synapses BDNF regulates endocannabinoid-mediated plasticity Liangfang Zhao, Mason Li-Wen Yeh and Eric S. Levine Department of Neuroscience, University of Connecticut Health Center, Farmington, CT 06030
منابع مشابه
Role for Endogenous BDNF in Endocannabinoid-Mediated Long-Term Depression at Neocortical Inhibitory Synapses
The endogenous cannabinoid (endocannabinoid) system is an important regulator of synaptic function. Endocannabinoids acutely modulate inhibitory and excitatory transmission, and also mediate long-term depression at GABAergic and glutamatergic synapses. Typically, endocannabinoid synthesis and release is stimulated by depolarization-induced calcium influx and/or activation of phospholipase-C (PL...
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The endogenous cannabinoid (endocannabinoid) system is an important regulator of synaptic function. Endocannabinoids acutely modulate inhibitory and excitatory transmission, and also mediate long-term depression at GABAergic and glutamatergic synapses. Typically, endocannabinoid synthesis and release is stimulated by depolarization-induced calcium influx and/or activation of phospholipase-C (PL...
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Learning and memory are thought to involve activity-dependent changes in synaptic efficacy such as long-term potentiation (LTP) and long-term depression (LTD). Recent studies have indicated that endocannabinoid-dependent modulation of inhibitory transmission facilitates induction of hippocampal LTP and that endocannabinoids play a key role in certain forms of LTD. Here, we show that repetitive ...
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تاریخ انتشار 2015